Clinicohistopathological Correlation of leprosy in a peripheral hospital of Mumbai.

Dr.Yasmeen Khatib; Dr.Surekha Khaire

Volume : V, Issue : XI, November - 2016

Clinicohistopathological Correlation of leprosy in a peripheral hospital of Mumbai.

Dr. Yasmeen Khatib, Dr. Surekha Khaire

Abstract :

Background -Leprosy a chronic infectious disease involving mainly skin and peripheral nerves presents with different clinicopathological forms. Aim -To correlate clinical and histological diagnosis of skin biopsies of leprosy using Ridley- Jopling classification Material and Methods- A prospective study was done on 54 cases of leprosy over a period of 2 years. Skin biopsies were studied for different histological features and fite stain was done to classify different types of leprosy .Clinicohistopathological Concordance rate was calculated . Result-In 54 cases of leprosy studied,we observed clinicohistopathological concordance was maximum in ENL(100%) followed by BT(58.2%), BL(50%), Lepra Reaction 1(50%),Histioid leprosy(50%), TT(44.44%), and least in IL(28.57%). Overall, it was 51.85%. Conclusion -Leprosy which is a major health problem in India can be reduced with the help of simple and important tool of histological and bacteriological examination for lepra bacilli , of skin biopsy and a good clinicopathological correlation .