CLINICO-MYCOLOGICAL PROFILE OF VAGINITIS IN REPRODUCTIVE AGE GROUP IN KOTA REGION

Dr KHUSHBOO SHARMA; Dr GHANSHYAM SONI; Dr SUCHITRA MORYA; Dr DEEPMALA NAHAR

Volume : VIII, Issue : V, May - 2019

CLINICO-MYCOLOGICAL PROFILE OF VAGINITIS IN REPRODUCTIVE AGE GROUP IN KOTA REGION

Dr Khushboo Sharma, Dr Ghanshyam Soni, Dr Suchitra Morya, Dr Deepmala Nahar

Abstract :

INTRODUCTION- Fungus is the second most common cause of Vaginitis. Hence the present study was undertaken to investigate the prevalence, risk factors, Isolation, identification & distribution of Candida spp., and to determine the susceptibility to commonly used antifungals. MATERIAL & METHOD- Vaginal swabs collected from 100 patients with history of white discharge and subjecting it to microscopy and culture. Susceptibility of the isolates to antifungal drugs was determined by disk diffusion method. RESULT- Candida as the causative agent of Vulvovaginitis was noted in 36% of cases. The incidence of candida were significantly high in pregnancy (46%), oral contraceptives (35%) & intrauterine devices (38%) users, infertility treatment (29%), post hysterectomy (25%) and diabeties (33%). Out of the 39 isolates, C.albicans were most common (69%) species. Overall resistance for Candida was 18% for Fluconazole, 26% for Itraconazole, 15% for Clotrimazole, 18% for Ketoconazole, 10% for Nystatin and 0% for Amphotericin B. CONCLUSION-The prevalence of candida was 36%. Risk factors for VVC are pregnancy, oral contraceptive, intrauterine devices, infertility treatment, post hysterectomy, and diabeties. The predominant species isolated was C.albicans. Amphotericin B and Nystatin proved to be the most effective drug in present study.