Clinical profile and management outcome of ocular myasthenia gravis in South Indian population

DR.P.SUBBA REDDY

Volume : VI, Issue : III, March - 2017

Clinical profile and management outcome of ocular myasthenia gravis in South Indian population

Dr. P. Subba Reddy

Abstract :

Myasthenia Gravis, is one of the most well defined forms of autoimmune disease, which involves the neuromuscular junction of skeletal muscles, resulting in weakness of skeletal muscles. The disease can be divided into adult onset and childhood onset. It is the most common disorder that affects the neuromuscular junction.Ptosis is the most common symptom in patients with ocular myasthenia. Females are more frequently affected in age group of less than 15 years and males above 15 years. Cogan�s lid twitch sign will be significantly present in myasthenic ptotic eye, irrespective of the grade of ptosis. Thus Cogan�s sign can be taken for the initial diagnosis of myasthenic eyes, which can be confirmed by ice pack test, neostigmine test etc. Myasthenia can be affected by environmental temperature. Treatment of myasthenia with pyriodstigmine alone shows significant improvement in patients.