Clinical And Epidemiological Study Of Bronchial Asthma In Children & Assessment Of Severity Of Asthma And Its Correlation With Serum IGE Levels

Sampath Kumar D; Sampath Kumar P; Priyadharshini

Volume : VII, Issue : II, February - 2018

Clinical And Epidemiological Study Of Bronchial Asthma In Children & Assessment Of Severity Of Asthma And Its Correlation With Serum IGE Levels

Sampath Kumar D, Sampath Kumar P, Priyadharshini

Abstract :

AIM - To assess the severity of Asthma; to estimate serum IgE levels and to compare the serum IgE levels in mild, moderate and severe grades of Asthma. .

METHOD- The study population included 75 children from those attending the outpatient as well as those admitted in the department of pediatrics of GMKMCH Salem with symptoms and sign suggestive of onchial asthma.Severity of asthma was assessed by clinical history and peak flowmetry and the cases where categorized into intermittent mild, moderate and severe grades of asthma based on global initiative for Asthma guidelines.Using Pathozyme Omega Diagnostics IgE Elisa kit serum IgE levels were measured.

RESULT- Serum IgE levels were increased in all 4 categories of asthma patients when compared to normal control groups. As the severity of asthma increased, the serum IgE levels also significantly increased.

CONCLUSION- IgE has found to play a predominant role both in the prevalence and severity of asthma