Volume : V, Issue : IV, April - 2016

BIOLOGICAL SCREENING OF SOME NEW METAL OXALATO COMPLEXES

Gaurav Varshney, Sunita Sharma

Abstract :

 It is now a truism that, in recent years that chemistry has experienced an impressive renaissance. Academic and industrial research in chemistry is flourishing and the field of co-ordination chemistry is growing exponentially, especially the complexation of transition metals with organic ligands. This paper describes the preparation and characterization of mixed ligand transition metal complexes of Cobalt (II) ions with di basic oxalic acid as primary ligand and heterocyclic amines as secondary ligands. Their conventional physical and chemical properties analyses have been done. On the basis of physico-chemical analysis and spectral studies metal complexes may be formulated as [M (OA) L2 ], where M stands for bivalent cobalt metal ion, OA for oxalate ion and L for heterocyclic amines, viz. pyridine, quinoline, iso-quinoline and 4-picoline. The complexes are quite stable coloured solid but spåly soluble in water. Magnetic moment values and spectral studies reveal the tetrahedral geometry to all the prepared complexes. The synthesized cobalt oxalate complexes with pyridine (C1 ), quinoline (C2 ), isoquinoline (C3 ) and with 4-picoline (C4 ) were screened by the disc diffusion method against the multi drug resistant fungal pathogen Fusarium oxysporum f. sp. lycopersici and Alternaria solani causing diseases in vegetable crops. In vitro antifungal screening indicates that the complexes show enhanced antifungal activities against the fungal strains as compared with parental compounds. Complex with 4- picoline (C4 ) as secondary ligand showed the highest antifungal activity

Keywords :

Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

Gaurav Varshney, Sunita Sharma BIOLOGICAL SCREENING OF SOME NEW METAL OXALATO COMPLEXES Global Journal For Research Analysis, Vol.5, Issue : 4 APRIL 2016

Number of Downloads : 471

References :