BIOAPIFIT ANTI-HEMORRHOIDAL OINTMENT EFFICIENCY - A COMPARISON WITH STANDARD APPROACH

Orescanin Visnja; Findri Gustek Stefica; Rodic Josipa

Volume : VII, Issue : IX, September - 2018

BIOAPIFIT ANTI-HEMORRHOIDAL OINTMENT EFFICIENCY - A COMPARISON WITH STANDARD APPROACH

Orescanin Visnja, Findri Gustek Stefica, Rodic Josipa

Abstract :

Hemorrhoids are defined as varicosities of the veins of the hemorrhoidal plexus, often complicated by inflammation, pain, thrombosis, and bleeding. The objective of this study wasto assess the efficacy of new Bioapifit^�multi-component ointment consisted of honey, Cera flava, glycerin,the oil macerates of Achilea millefolium L., Plantago major L., Quercus robur L., Salvia officinalis L., Olea europaea L., Polygonum aviculareL., Calendula officinalis L., Matricaria chamomilla L. andessential oils of Melaleuca alternifolia, Thymus vulgaris ct. Thymol and Origanum vulgare for the treatment of hemorrhoids of grade 1 to 3 as well as the comparison to the standard treatment approach. The experimental group consisted of 66 participants was treated with Bioapifit^� ointment while the control group consisted of 40 participants was treated with Faktu^� ointment (50 mg/g of policresulene and 10 mg/g of cinchocaine). Either Bioapifit^� or Faktu^�ointment was applied externally three times a day for ten days onto clean perianal area and rectally once a day (before bedtime) using appropriate applicator. The evaluation of the patients before and following the therapy was done in terms of pain, defecation discomfort, bleeding severity, anal itching severity and overall subjective discomfort. After three days of the therapy the mean values and standard deviations in the experimental group for pain, defecation discomfort, bleeding, itching and overall subjective discomfort decreased from 6.6�0.9, 6.9�1.0, 2.2�0.7, 2.6�0.6and 7.0�0.8, respectively to2.2�0.8, 2.5�1.0, 0.6�0.5, 1.3�0.7 and 3.0�0.8, respectively. At 10^th day of the treatment all five parameters were graded 0 by all 66 patients. The control group also showed a significant decrease of all five parameters after only three days of the therapy while in the end of the treatment overall subjective symptoms decreased from 3.8�1.0 to 0.9�0.9. Bioapifit^� ointment was found superior to Faktu^�ointment in the treatment of the symptoms of hemorrhoidal disease.