Volume : IV, Issue : IV, April - 2015
Bio-Clinical Study of Envenomed victims in Osmania General Hospital, Hyderabad.
Dr. C. R. Ram Reddy, Dr. C. R. Vijay Bharath Reddy
Abstract :
<p>&lt;p&gt;&amp;nbsp;Background &amp;amp; Objectives: Every year there are about one lakh cases of snake bite deaths all over the world, mostly either&amp;nbsp;&lt;/p&gt; &lt;div&gt;with coa, viper or krait snakes. Nearly about 1/3rd of them are reported in India. Still most of the rural population of&amp;nbsp;&lt;/div&gt; &lt;div&gt;India needs awareness regarding envenomation management. About 40% of snake bitten victims are losing their lives&amp;nbsp;&lt;/div&gt; &lt;div&gt;ignorantly due to delayed hospitalization and indulging in unscientific management. Sole object of this study is to project and impress upon the&amp;nbsp;&lt;/div&gt; &lt;div&gt;scientific management through clinical evaluation, study of bio&amp;ndash;clinical samples with subsequent treatment of envenomed victims.&lt;/div&gt; &lt;div&gt;Methods:&lt;/div&gt; &lt;div&gt;Various types of data concerning 276 snake bite victims both live and dead cases were collected from retrospective, prospective and follow&amp;ndash;up&amp;nbsp;&lt;/div&gt; &lt;div&gt;cases for coa bite detection during the period from 1999 to 2000. The live cases are followed clinically in the casualty, medical wards and ICU.&amp;nbsp;&lt;/div&gt; &lt;div&gt;Dead victims are examined in the mortuary of Osmania General Hospital, Hyderabad; A.P. Antibodies against coa venom are raised while&amp;nbsp;&lt;/div&gt; &lt;div&gt;conducting animal experimentations (rabbits and goats) and subjected the anti body sera to ELISA test against bio&amp;ndash;samples of victims. Live bioclinical samples collected from the clinical wards are bitten area washings, blood, urine and cereo spinal fluid (csf) for further investigations.&amp;nbsp;&lt;/div&gt; &lt;div&gt;From the mortuary snake bite victim&amp;rsquo;s autopsy samples like skin bit, blood from right ventricle, liver and kidney are collected. All the samples are&amp;nbsp;&lt;/div&gt; &lt;div&gt;subjected to ELISA, histopathological examination and other routine investigations.&amp;nbsp;&lt;/div&gt; &lt;div&gt;Results:&amp;nbsp;&lt;/div&gt; &lt;div&gt;The results obtained in this study of envenomed victims of live and dead are analyzed, compiled and compared and they are found to be satisfied&amp;nbsp;&lt;/div&gt; &lt;div&gt;in their respective criterions. The same results are further strengthened with the observations of previous scientific studies mentioned later in the&amp;nbsp;&lt;/div&gt; &lt;div&gt;discussion part.&amp;nbsp;&lt;/div&gt; &lt;div&gt;Conclusion&amp;nbsp;&lt;/div&gt; &lt;div&gt;The clinical evaluation, biochemical and histopathological examination of all snake bite cases living and dead under the study have shown much&amp;nbsp;&lt;/div&gt; &lt;div&gt;convincing and corroborating evidences with one another. The results of the study are very much comparable and are consistent with previous&amp;nbsp;&lt;/div&gt; &lt;div&gt;scientific observations as expressed in discussions.&lt;/div&gt;</p>
Keywords :
envenom victims fang marks snake bite deaths ELISA histopathological examination neuroparalysis cellulites renal failure cobra antibodies in rabbit.
Article:
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DOI : https://www.doi.org/10.36106/gjra
Cite This Article:
Dr. C.R.Ram Reddy, Dr. C. R. Vijay Bharath Reddy BIO–CLINICAL STUDY OF ENVENOMED VICTIMS Osmania General Hospital, Hyderabad Global Journal For Research Analysis, Vol: 4, Issue: 4 April 2015
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Dr. C.R.Ram Reddy, Dr. C. R. Vijay Bharath Reddy BIO–CLINICAL STUDY OF ENVENOMED VICTIMS Osmania General Hospital, Hyderabad Global Journal For Research Analysis, Vol: 4, Issue: 4 April 2015