Association between serum uric acid and non-alcoholic fatty liver disease in a tertiary care center in northern Kerala, India

Dr. Seebu Valiyakath; Dr. Junise M

Volume : IV, Issue : XII, December - 2015

Association between serum uric acid and non-alcoholic fatty liver disease in a tertiary care center in northern Kerala, India

Dr. Seebu Valiyakath, Dr. Junise M

Abstract :

<p>Background: The role of elevated serum uric acid level in patients with NAFLD is increasingly noted. This study intends to determine association between NAFLD and SUA levels in healthy subjects who electively attended health checkups our hospital. Methods: Among 3342 subjects who attended health checkups during the period of November 1 2014 to October 31 2015; 1884 subjects without other risk factors were enlisted in our study. We calculated the odds ratio of NAFLD by sex specific quartile of SUA. Result: The proportion of NAFLD was 29.4% (33.9% in men and 23.5% in women). After adjusting the age the ORs (95% CI) for NAFLD according to each quartile of uric acid were 1.00, 1.32, 1.97, 2.82 for men and 1.0, 0.97, 1.25, 3.01 for women. Conclusion: High SUA levels are associated with an increased risk of development of NAFLD</p>