ASSESSMENT OF MAJOR RISK FACTORS ASSOCIATED WITH PERIPHERAL VASCULAR DISEASE: A CASE-CONTROL STUDY

Dr. Kamalesh Inteti; Dr. M.M.Rehman

Volume : IX, Issue : V, May - 2020

ASSESSMENT OF MAJOR RISK FACTORS ASSOCIATED WITH PERIPHERAL VASCULAR DISEASE: A CASE-CONTROL STUDY

Dr. Kamalesh Inteti, Dr. M. M. Rehman

Abstract :

Objectives: To assess the major risk factors which are potentially contributing to peripheral vascular disease (PVD). Methods: This is a case-control study conducted among inpatients of a Tertiary care hospital in the state of Andhra Pradesh who are having the risk factors that contribute to PVD. Cases and controls were selected based on the ABPI (Ankle Brachial Pressure Index). A total of 50 cases and 100 controls were included in the study i.e., in 1:2 ratio. The odds of exposure of PVD to risk factors were assessed using odds ratio. Results: In our study, we found that the maximum number of cases were among the age group of 51-60 years. Smoking and Alcoholism showed significantly higher odds of exposure than all others with a P-value <0.0001. Diabetes and CAD also showed significant risk with P-Values of 0.005 and 0.027 respectively. Hypertension and Platelet count posed lesser risk with P-values of 0.728 and 0.2201 respectively. Gender difference imposed insignificant odds with a P-Value of 0.550. Conclusion: As per the results, we demonstrate that increased risk of PVD is associated with advanced age. Sex is not having any predominant association with disease i.e., both males and females are equally prone to the disease. Alcohol and Smoking are major risk factors and the risk of disease increases with increased duration. Among diabetics, type ii diabetes contributes to increased risk of PVD. Hypertension and Dyslipidemia also contribute to the pathogenesis of PVD but not that much affiliated as others. there is a clearcut observation that the trend is shifting towards Diabetes from Smoking.