Assessment of Intervention of Antibiotics among patients with Preterm Premature Rupture of Membrane in a Tertiary Hospital of Kolkata, India

Dr. Papia Saha; Dr. Palash Das

Volume : VIII, Issue : IV, April - 2019

Assessment of Intervention of Antibiotics among patients with Preterm Premature Rupture of Membrane in a Tertiary Hospital of Kolkata, India

Dr. Papia Saha, Dr. Palash Das

Abstract :

Introduction: Preterm Premature Rupture of Memane can lead to significant perinatal mortality and morbidity. Materials and Methods: An intervention study was conducted with two different regimens of antibiotic on two randomized groups. Data were analysed by Students �t� test, Chi square test using SPSS version 20.0. Results: Majority were in the age group of 21 to 30 yrs, second gravid. Nulliparous and multiparous mothers were equally distributed. Mean duration (hrs) since rupture of memanes was 7.88 � 3.83 hrs in group A and 9.16 � 4.18 hrs in group B. Latency of 7 days and less was seen in 22.8% of group A population and 15.8% of group B population respectively. Azithromycin and Erythromycin groups have been observed with equal maternal and neonatal outcomes. Side-effects were found low among patients. Conclusion: There was no statistical difference in outcomes between two groups of antibiotic regimens in term of latency, maternal and neonatal outcome.