ANTIOXIDANT ACTIVITY OF ADATHODAI CHOORANAM BY IN-VITRO APPROACH

Vethamerlinkumari.H; Karthikeyan.Karu; Nalinisofia.H; Manickavasakam.K; Banumathi.V

Volume : VII, Issue : II, February - 2018

ANTIOXIDANT ACTIVITY OF ADATHODAI CHOORANAM BY IN-VITRO APPROACH

Vethamerlinkumari. H, Karthikeyan. Karu, Nalinisofia. H, Manickavasakam. K, Banumathi. V

Abstract :

The Siddha poly herbal drug Adathodai Chooranam is indicated for respiratory disorders like Bronchial Asthma, onchitis, COPD etc. Bronchial asthma is a clinical syndrome with possible correlation to oxidative stress; therefore the effectiveness of some antioxidant drugs has been studied in management of chronic onchial asthma. Antioxidants can compensate the oxidative stress that correlates with asthma, can reduce the symptoms of asthma, and improve pulmonary functions.¹This study was also intended to explore the anti-oxidant activity of the Adathodai Choorananam by in-vitro methods. The antioxidant capacity of the drug was evaluated with the estimation of total Flavonoids, estimation of total phenols, estimation of Vitamin C, DPPH spectrometric assay, Metal chelating assay, Assay of catalase, Lipid peroxidation assay, and assay of glutathione peroxidase. In DPPH method, 100 �g/ml of the drug and ascorbic acid exhibit 98.9% and77.7% inhibition respectively and the IC 50 value of the drug is