ANTI BACTERIAL EFFECT OF SILVER NANOPARTICLE ON MRSA ISOLATES FROM ORAL INFECTIONS

Dr.Zameer Pasha; Dr.Savina Gupta; Dr. Nazia Khan

Volume : VII, Issue : VI, June - 2018

ANTI BACTERIAL EFFECT OF SILVER NANOPARTICLE ON MRSA ISOLATES FROM ORAL INFECTIONS

Dr. Zameer Pasha, Dr. Savina Gupta, Dr. Nazia Khan

Abstract :

Aim of our study is to evaluate the antibacterial activity of silver Nano particle(Ag-NPs) against MRSA strains recovered from patients with oral infections

Material and Methods:- Samples were collected from Patients attending department of oral and maxillofacial surgery, Jaipur dental college who were diagnosed with oral infections. The samples were subjected to culture and sensitivity and MRSA (Methicillin resistant Staphylococcus aureus) screening. MRSAstrains were treated with Ag-Nanoparticles to know the antibacterial affect

Results:- Out of 146 samples, 26 specimens showed Methicillin-resistant S aureus (MRSA) The MIC and MBC values of Ag-NPs against MRSA strains were observed to be very low (i.e. in the range of 12.5-100 μg/ml), indicating very well bacteriostatic (represented by the MIC) and bactericidal activity (represented by MBC).

Conclusion:- In recent years, there is increase in MRSA in oral and perioral samples with emergence of new resistant strains of MRSA. In our study we have seen Ag-NPs size 5-10nm has inhibited growth of Methicillin Resistant Staphylococcus aureus in vitro at nontoxic concentration, which makes it to use as anti-bacterial agent in oral infections