Analgesic activity of ethanol extract of stem bark extract of Zyziphus xylopyrus by using Tail Flick Latency model in rats.

Dr Gujaram Marandi; Dr Pravin Dhone

Volume : IX, Issue : I, January - 2020

Analgesic activity of ethanol extract of stem bark extract of Zyziphus xylopyrus by using Tail Flick Latency model in rats.

Dr Gujaram Marandi, Dr Pravin Dhone

Abstract :

Context:. Zizyphus xylopyrus (Retz.) is found throughout North- Western India, Pakistan and China. Aims: to study Analgesic activity of ethanol extract of stem bark extract of Zyziphus xylopyrus by using Tail Flick Latency model in rats. Settings and Design: This was a longitudinal study done on 30 no. Wistar rats done in post graduate Department of Pharmacology, VIMSAR, Burla Methods and Material:. Tail Flick Latency model Statistical analysis used: One way ANOVA followed by Dunnett�s test. Results: EEZX 200 and 400 mg/kg showed significant increase in tail flick latency parameters. Conclusions: These results suggest that EEZX at 200 & 400 mg/kg doses possesses significant analgesic effect, however more studies are recommended.