Analgesic activity of ethanol extract of stem bark extract of Zyziphus xylopyrus by using Acetic acid induced Writhing model in mice.

Dr Gujaram Marandi; Dr Pravin Dhone

Volume : IX, Issue : I, January - 2020

Analgesic activity of ethanol extract of stem bark extract of Zyziphus xylopyrus by using Acetic acid induced Writhing model in mice.

Dr Gujaram Marandi, Dr Pravin Dhone

Abstract :

Context:. Zizyphus xylopyrus (Retz.) is found throughout North- Western India, Pakistan and China. Aims: to study Analgesic activity of ethanol extract of stem bark extract of Zyziphus xylopyrus by using Acetic acid induced Writhing model in mice. Settings and Design: This was a longitudinal study done on 30 no. swiss albino mice done in post graduate Department of Pharmacology, VIMSAR, Burla Methods and Material: Acetic acid induced writhing model. Statistical analysis used: One way ANOVA followed by Dunnett�s test. Results: EEZX 200 and 400 mg/kg showed significant decrease in number of writhes in Acetic acid induced Writhing model Conclusions: These results suggest that EEZX at 200 & 400 mg/kg doses possesses significant analgesic effect, however more studies are recommended.