Anaemias in HIV-Infected Individuals during antiretroviral Therapy and its Implications.

Sudhakar Merugu; Madhukar Reddy Kadaru

Volume : IX, Issue : V, May - 2020

Anaemias in HIV-Infected Individuals during antiretroviral Therapy and its Implications.

Sudhakar Merugu, Madhukar Reddy Kadaru

Abstract :

whether the type of anemia in persons living with HIV/AIDS changed from the beginning of highly antiretroviral therapy (HAART) and had implications for treatment outcomes . Repeated measures linear estimated the anemia-type associated change in the CD4 cell-count, over 18 months. Estimated associations between anemia-type and time to (a) gain at least 100 CD4 cells/L . Among the 1900 with anemia at the study end, 85.3% (n = 1719) had macrocytic anemia, 12.8% (n = 300) had ACD and 2.0% (n = 200) had microcytic anemia. A substantial decline in ACD and microcytic anemia occurred in tandem with large increase in macrocytic anemia over 18 months on HAART. Interventions to mitigate all anemia�particularly ACD, is expected to improve the immune recovery rate.