AN EVALUATION OF THE EFFICACY OF ASPIRIN AND BENZYDAMINE HYDROCHLORIDE GARGLE FOR ATTENUATING POSTOPERATIVE SORE THROAT�

Dr Varun Naik; Dr Harprit Kaur Madan; Dr Anita Shetty; Dr Nandini Dave

Volume : V, Issue : IV, April - 2016

AN EVALUATION OF THE EFFICACY OF ASPIRIN AND BENZYDAMINE HYDROCHLORIDE GARGLE FOR ATTENUATING POSTOPERATIVE SORE THROAT�

Dr Varun Naik, Dr Harprit Kaur Madan, Dr Anita Shetty, Dr Nandini Dave

Abstract :

<p>&nbsp;Aim: The present study was carried out to compare the efficacy of preoperative Aspirin and Benzydamine Hydrochloride gargle for attenuating POST in patients undergoing elective surgery (e.g. mastoidectomy, modified radical mastectomy, fioadenoma excision etc.) under GA with oral endotracheal intubation. Material and methods: The present study was carried out on in a tertiary care teaching hospital in 90 patients. Patients were randomly allocated into 3 group of 30 patients each. Group AS-Aspirin, Group BH-Benzydamine Hydrochloride, Group C-control. Patients were asked to do gargle the study drug for 30 secs 5 mins prior induction of anesthesia. POST was assessed at 0, 2, 4 and 24 hours post surgery. Results: The results were collected tabulated and analyzed using the chi square, Mann Whitney test and Kruskal Wallis Test. The overall incidence of POST in C group (80%) was reduced to (23.33%) in AS group and (20%) in BH group. This was statistically significant. Conclusion: In conclusion, both Aspirin and Benzydamine Hydrochloride gargles are safe, simple and effective means of reducing the incidence and severity of POST; but benzydamine hydrochloride gargle is more effective than Aspirin gargle in reducing POST for longer duration.</p>