Volume : VII, Issue : VIII, August - 2018

ADVERSE EVENTS AMONG PATIENTS OF DRUG RESISTANT TUBERCULOSIS IN INTENSIVE PHASE RECEIVING SECOND LINE ANTI TB TREATMENT

Dr. Rohit Walse, Dr. Mangala Borkar Sonavani

Abstract :

 Setting- A DR-TB (Drug Resistant-Tuberculosis) Tertiary Care Center At GMC Aurangabad.

Objective: To detect adverse effects of drugs used in drug resistant tuberculosis in intensive phase at the earliest to
improve compliance.
Design: A cross sectional prospective study.
Results: Out of 151 DR TB patients 50.33% patients developed adverse drug events of which gastro intestinal (nausea-21.19%, vomiting-
18.54% & 14.56%) manifestations were most common followed by arthralgia (13.90), psychiatric manifestations (insomnia-10.59% &
depression-1.32%), injection site swelling/pain (8.6%), impaired heå (1.32%) and rash (0.66%).
Conclusions: Gastrointestinal symptoms are the most common adverse drug events. Taking the pills embedded in banana, pedha or
mashed potato along with spacing of drugs and proper guidance helps in reducing gastrointestinal symptoms. Maximum number of
adverse events occur in the 􀃶rst 2 months and intensive counseling to patients and caregivers is essential to prevent defaulting.

Keywords :

Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

Dr. Rohit Walse, Dr. Mangala Borkar Sonavani, ADVERSE EVENTS AMONG PATIENTS OF DRUG RESISTANT TUBERCULOSIS IN INTENSIVE PHASE RECEIVING SECOND LINE ANTI TB TREATMENT, GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-7 | Issue-8 | August-2018


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