Acute Transvere Myelitis Following Japanese Enchephalitis Viral Infection : A Rare Presentation Of The Infection

Dr. Neil B. Palkhiwala; Dr. Tanvi R. Seth; Dr. Ami P. Parikh; Dr. Harsh V. Khatri

Volume : V, Issue : XII, December - 2016

Acute Transvere Myelitis Following Japanese Enchephalitis Viral Infection : A Rare Presentation Of The Infection

Dr. Neil B. Palkhiwala, Dr. Tanvi R. Seth, Dr. Ami P. Parikh, Dr. Harsh V. Khatri

Abstract :

Japanese encephalitis (JE) is an important cause of epidemic encephalitis in southeast Asian countries. A huge population living in the endemic regions makes this disease a global health concern. JE is caused by Japanese encephalitis virus (JEV), a mosquito-borne virus, Single stranded positive sense RNA virus belonging to the genus Flavivirus (family Flaviviridae). WHO estimated that approximately 67,900 JE cases typically occur annually in the 24 JE-endemic countries, for an incidence of 1.8 per 100?000 overall. In India, many outeaks of JE have been reported since 1955. [1] Apart from encephalitis, immune-mediated manifestation as acute transverse myelitis (ATM) have been rarely previously reported in JE. The case mentioned here is a male patient presented with acute-onset bilateral lower limb weakness followed by upper limb weakness without any signs of altered mentation. MRI cervico-dorsal Spine findings suggested Signal Intensity Alterations from the C2 to D10 levels. Corticosteroid pulse therapy for 5 days showed Improvements in power with complete recovery of other symptoms as well.