ACASE REPORT OF MEDULLARY THYROID CARCINOMA: CYTOLOGICAL FEATURES AND THE ROLE OF PROCALCITONIN IN PREOPERATIVE DIAGNOSIS

DR SREECHITHRA KARTHA; DR AJITH RAJAN; Mr UMESH S.P

Volume : VI, Issue : VII, July - 2017

ACASE REPORT OF MEDULLARY THYROID CARCINOMA: CYTOLOGICAL FEATURES AND THE ROLE OF PROCALCITONIN IN PREOPERATIVE DIAGNOSIS

Dr Sreechithra Kartha, Dr Ajith Rajan, Mr Umesh S. P

Abstract :

Medullary thyroid carcinoma (MTC) is an unusual neuroendocrine thyroid neoplasm.Cytological diagnosis is difficult,as other thyroid neoplasms can mimicMTConfine needle aspiration cytology (FNAC).We present a case of MTCwhere the diagnosis was established by FNAC and semi-quantitativeprocalcitonin assay.FNAC showed a dispersed cell pattern,plasmacytoid morphology,cytoplasmic granules, and speckled chromatin. Calcitonin,the specific biomarker for MTC,has many drawbacks,which prompted us to measure serum procalcitonin.We are reporting this novel case because serum procalcitonin, a sepsis marker, is not routinely used as a marker for MTC.