ABILITY OF GINGER IN AMELIORATING CHEMOTHERAPY INDUCED NAUSEA IN HEMATOLOGICAL AND SOLID MALIGNANCIES

Mathur Ashwin; Agarwal VK

Volume : VII, Issue : II, February - 2018

ABILITY OF GINGER IN AMELIORATING CHEMOTHERAPY INDUCED NAUSEA IN HEMATOLOGICAL AND SOLID MALIGNANCIES

Mathur Ashwin, Agarwal Vk

Abstract :

Aims and Objectives:Effect of ginger on chemotherapy induced side effects were assessed by complete blood counts, renal function test, liver function test, grading of nausea, vomiting, mucositis and feile neutropenia in patient of hematological and solid malignancies.

Materials and Methods: This is a Observational case control study in which 40 Cases received chemotherapy plus standard antiemetics plus ginger and 40 Controls received chemotherapy plus standard antiemetics only.

Patients were randomized by computer generated random number table and ginger was started in dose of 1.5 gm/day in three divided doses from first day of chemotherapy up to 4 days.

All the cases were evaluated in follow-up visits at 1, 2 & 4 week.

Results:

Statistically significant effects were observed in improvement of chemotherapy induced Nausea in patients. No significant differences were found in hemoglobin, total leukocyte count, platelet count, blood urea, s. creatinine, total bilirubin, SGOT, SGPT, in grading of vomiting, oral mucositis and feile neutropenia.

Conclusions: In this study authors conclude that ginger significantly reduces chemotherapy induced nausea.