A STUDY TO COMPARE ANALGESIC EFFECT OF BUPRENORPHINE PATCH AND ORAL TAPENTADOL IN KNEE OSTEOARTHRITIS RELATED CHRONIC PAIN

Kulsaurabh; Dr Rajmala; Dr Kulgaurav; Dr Geeta Ahlawat

Volume : VIII, Issue : I, January - 2019

A STUDY TO COMPARE ANALGESIC EFFECT OF BUPRENORPHINE PATCH AND ORAL TAPENTADOL IN KNEE OSTEOARTHRITIS RELATED CHRONIC PAIN

Kulsaurabh, Dr Rajmala, Dr Kulgaurav, Dr Geeta Ahlawat

Abstract :

Osteoarthritis is a common chronic degenerative condition of joints in adult population, commonly affecting the hip and knee joints. It is a common cause of pain and difficulty in walking and has heavy impact on day to day life style and represents an ever-increasing burden on health care. Osteoarthritis is a slowly evolving articular disease characterized by a gradual development of joint pain, stiffness, and loss of full range of motion.. The main goals in management of OA are pain control and improvement in joint function and health-related quality of life. The approaches recommended for the management of knee OA are surgical and non surgical. Pharmacological treatment includes administration of non-steroidal anti-inflammatory drugs (NSAIDS) oral or topical, glucosamine, chondroitinsulphate and opioids (oral or patches),etc. We carried out a study over 50 patients divided in two groups (25 each ) over a period of 4 weeks to compare analgesic effects of Buprenorphine patch (group B ) and Tab Tapentadol ( group T ) . Low-dose 7 days buprenorphine transdermal patch and tab. Tapentadol were good treatment modality in OA knee for management of symptomatic osteoarthritis knee. Both the two drug provided good pain relief and improvement in physical disability to the patients in terms of improvement in pain score, physical status, quality of life and patient satisfaction. However decrease in pain score and improvement in WOMAC Index was significant in all the two groups with slightly better results in group B.