A study on Doppler parameters of Hepatic artery and severity of liver disease

Dr.R.Karthikeyan; Dr.B.Sivasubramaniam; Dr.E.Kandasamy alias Kumar

Volume : VI, Issue : VII, July - 2017

A study on Doppler parameters of Hepatic artery and severity of liver disease

Dr. R. Karthikeyan, Dr. B. Sivasubramaniam, Dr. E. Kandasamy Alias Kumar

Abstract :

Aim:To compare the Doppler parameters such as Hepatic artery Pulsatile indices ( PI) and Resistive indices (RI) with clinical and Histological parameters in cirrhotics patients to assess the severity of liver disease.MATERIALS AND METHODS:This is a prospective study done in Department of Medical Gastroenterology in Rajiv Gandhi Government General Hospital Chennai. The study was carried during the period June 2013- March 2014. Patients with compensated cirrhosis involved in the study. Patients with comorbid conditions such Intrinsic Renal disease, Diabetes and Hypertension were excluded.Patients with serum creatinine more than 1.4 mg.Patients with malignancy.Doppler parameters such as HI and RI were assessed in all patients. Clinical and Histological parameters were also assessed.Statistical analysis was done by SPSS 16 software. RESULTS In our prospective study, total of 30 pts of compensated cirrhosis were enrolled. There were 23 males and 7 females. The mean age of presentation was 45.3 years.. Pulsatile index and Resistive indices of Hepatic artery calculated.After evaluation of coagulation profile, these pts were subjected to liver biopsy. Total no of pts enrolled in this study was 30. Out of this, persons in age group 20- 40 were 10.33%. Those in age group 40- 65 accounted to about 20.67%. Mean age of patients was 45.3 years.In the 30 pts enrolled, 23 were males and 7 were females. In our study 24 out of 30 had episode of UGI bleed, other 6 were non bleeders. The median Hemoglobin was 9.3 gm%. The average platelet count was 63,900. The patients were subjected to OGD scopy, 26 pts had varices ranging from Gr1-3. 4 had no varices.The average Hepatic artery PI was 2.1997 and RI was 0.6910. Conclusion:Our study also showed significant correlation between AST & HA -PI . The inference from our study was higher the Pulsatile index, higher is the AST and more is severity of fiosis and liver disease. We also found no correlation between platelet count and HA-PI in our study.