A STUDY ON COMPARISION OF INTRAVENOUS LIGNOCAINE VERSUS GRANISETRON TO ALLEVIATE PAIN ON PROPOFOL INJECTION

Dr. Narendra Kumar Kalia; Dr. Pankaj Wadhwa

Volume : IX, Issue : VIII, August - 2020

A STUDY ON COMPARISION OF INTRAVENOUS LIGNOCAINE VERSUS GRANISETRON TO ALLEVIATE PAIN ON PROPOFOL INJECTION

Dr. Narendra Kumar Kalia, Dr. Pankaj Wadhwa

Abstract :

BACKGROUND: Induction agents are drugs that, when given intravenously in an appropriate dose, cause a rapid loss of consciousness. Propofol, 2,6-diisopropylphenol is most popular induction agent with its favourable characteristics of rapid and smooth induction and recovery, decrease incidence of nausea and vomiting METHODS: This is a double blind randomized controlled trial and patients were recruited after obtaining the consent. We included 100 subjects aged between 18-60 years, chosen for elective surgery under general anesthesia. These subjects were divided into Group I and Group II, comprising of 50 each. Patients of group I received 30mg lignocaine (3ml of 1% solution) IV and group II received 2mg (3ml) of granisetron IV and, over a period 5 seconds about 5 minutes after cannulation. RESULTS: A total of 100 cases were included in our study, who had been posted for the surgical procedures. The pain after propofol administration was absent in 72% and 64% patients of group I and group II respectively. Nearly 14% of the group I patients and 18% of group II patients had mild pain, while this percentage was 14% and 18% for moderate pain. None of the patients in both the groups had severe pain. CONCLUSIONS: The results of study, conclude that granisetron decreases the propofol induced pain as effectively as lignocaine and both the drugs did not differ in their effect on hemodynamic factors after the induction with propofol.