A STUDY OF VITAMIN D LEVELS IN PATIENTS WITH CHRONIC LIVER DISEASE

Md Ziauddin; Abeer Masood; Sheelu S.Siddiqi

Volume : VIII, Issue : XII, December - 2019

A STUDY OF VITAMIN D LEVELS IN PATIENTS WITH CHRONIC LIVER DISEASE

Md Ziauddin, Abeer Masood, Sheelu S. Siddiqi

Abstract :

INTRODUCTION- Chronic liver disease (CLD) is major sources of morbidity and mortality all over world, it accounts for about 2% of all deaths in Europe (170,000/year) with increasing mortality rates in several countries. Recent study on multiethnic cohort at United States has shown non alcoholic fatty liver disease (NAFLD) is the most common cause of CLD in all ethnic groups combined (52%), followed by alcoholic liver disease .Since, liver contributes an important role in the metabolism process of Vitamin D , consequently chronic diseases of the liver interfere with production of the active metabolites of vitamin D,. AIM- To study and examine the status of Vitamin D in relation to patients presenting with Chronic liver diseases METHODOLOGY - The present study was undertaken from July 2012 till June 2014 at, Department of medicine, Jawaharlal Nehru Medical College and Hospital, Aligarh Muslim University and Rajiv Gandhi Centre for Diabetes and Endocrinology, AMU, Aligarh. In the present study we examined 100 patients with diagnosed chronic liver diseases and /or cirrhosis .The patients recruited in our present study were enrolled after taking informed consent from them. Vitamin D was also estimated. CONCLUSION - Our findings suggest that periodic screening of serum vitamin D and supplementation should be considered in routine care of CLD patients, with emphasis given to patients with cirrhosis, however, safety and cost effectiveness need to be evaluated