A STUDY OF SERUM FASTING LIPID PROFILE AND SERUM TOTAL PROTEIN AND FRACTIONS IN NORMOTENSIVE NON-DIABETIC GLAUCOMA PATIENTS

Meenakshi Saikia; Jadab Kishore Phukan; Bharati Gogoi; Rohini Kanta Goswami

Volume : V, Issue : VI, June - 2016

A STUDY OF SERUM FASTING LIPID PROFILE AND SERUM TOTAL PROTEIN AND FRACTIONS IN NORMOTENSIVE NON-DIABETIC GLAUCOMA PATIENTS

Meenakshi Saikia, Jadab Kishore Phukan, Bharati Gogoi, Rohini Kanta Goswami

Abstract :

 Glaucoma, which is the third most common cause of blindness and is responsible for 10% of blindness worldwide, the majority of those affected in developing countries are unaware that they have the disease and visual impairment. This study was done to asses and compare serum fasting lipid profile, serum total protein and fractions concentration in normotensive, non-diabetic glaucoma patients with special reference to normotensive, non-diabetic glaucoma healthy controls. Mean total cholesterol value in glaucoma patients and controls were (162.52 ± 30.72) mg/dl and (137.07 ± 28.09) mg/dl respectively which is statistically significant (p < 0.001). Mean LDL-C value between glaucoma patients and controls were (94.68 ± 24.60) mg/dl and (69.08 �‚�24.05) mg/dl respectively and this difference was statistically highly significant (<0.001). The mean total protein value in cases and controls were (7.08 �‚� 0.54) gm/dl and (7.89 ± 0.33) gm/dl and respectively which is a significant differences (p < 0.01). Mean albumin value in cases and controls were (3.23 ± 0.31) gm/dl and (4.09 ± 0.34) gm/dl respectively which is also statistically significant (p < 0.01). There was significant increase in total cholesterol and LDL-C in glaucoma patients compared to controls. However, no significant difference in TGL-C, VLDL-C and HDL-C has been seen between the two groups. It was observed that both the total proteins and serum albumin were decreased in the patients group in comparison to controls group of the study population.