A STUDY OF HEPATITIS-C  PREVALENCE IN CKD PATIENTS ON MAINTANCE HEMODIALYSIS;A SINGLE CENTRE STUDY

RAJARAM BARDE; SUDHA ALAWE; UMESH VARYANI; PAVAN WAKHARE

Volume : V, Issue : III, March - 2016

A STUDY OF HEPATITIS-C PREVALENCE IN CKD PATIENTS ON MAINTANCE HEMODIALYSIS;A SINGLE CENTRE STUDY

Rajaram Barde, Sudha Alawe, Umesh Varyani, Pavan Wakhare

Abstract :

Introduction: Hepatitis C infection & CKD major health burden worldwide .wide range of extra-hepatic manifestations in various organs including the kidneys. HCV is both a consequence and cause of CKD.Hemodialysis in supporting the ESRD patients ,but carries a risk for hepatitis C infection. Despite much improvement the prevalence of hepatitis C infection in hemodialysis patients is still higher than the general population. Hepatitis C infection has a negative effect on the survival of hemodialysis and renal transplant patients. in developing countries with high prevalence of HCV, nosocomial transmission through transfusions, hemodialysis or unsafe injections is still an important issue Aim: The objective of study to assess the prevalence of hepatitis-c in CKD patients on maintenance hemodialysis . Materials and Methods: This is a prospective cross sectional in which 400 Hemodialysis CKD patients , who attended Dialysis units of Department of Nephrology, at Smt. G. R. doshi & Smt. K. M. Mehta, IKDRC, DR H. L.Trivedi ITS Ahmedabad (India)from period december2014 to october 2015.we performed elisa for hepatitis-b,hepatitis-c and hiv routinely in ourCKD patients on MHD on regular interval. All patients on maitanance hemodialysis were tested for anti-HCV antibodies[third generation]. Results: The overall prevalence of HCV infection was 6.25%. The longer the patient is on HD the more susceptible he/she is to HCV acquisition. Conclusion: managment of hep c in ckd on dialysis pts is challanging Hemodialysis is supporting ,but carries a risk for hepatitis C infection. HD patients should be routinely screened for HCV infection, preferably using serological methods. Strict adherence to universal precautions without isolating HCV-infected dialysis patients seems to be enough to control disease spread in HD units