Volume : IX, Issue : I, January - 2020

A REVIEW ON SOLID DISPERSION MULTILAYERED CAFEINE-CURCUMIN GRANULATED TABLET

Simanchal Panda

Abstract :

Caffeine is a diuretic, antihypertensive, analgesic component. Caffeine is widely used as popular analgesic in gradient. Curcumin is derived from curcuma longa belonging to family Zingiberaceae. It is one of the popular chemical constituent having antiulcer effect. Here it is an attempt to enhance bioavaibility by formulation as solid dispersion granulated tablets. The initial stage ulcer patients can relieve pain and with a herbal wound healing effect of curcumin may result in eradication of peptic wound. Curcumin can be extracted by cold percolation method with acetone. And caffeine can be extracted from Cofea Arabica plant with boiling with water followed by chloroform swirling in separating funnel. Organic part can be removed by evaporation and caffeine can be collected out. Solid dispersion can be prepared by different grades of polymers like HPMC , PVP with urea. The solid dispersion has a capability of high dissolution rate. Rate of release from formulation can be studied by dissolution. The drug polymer stability can be studied by keeping them at various humidity range and temperature. FTIR and XRD may confirm the formulation and fusion of drug in polymer.

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Article: Download PDF    DOI : https://www.doi.org/10.36106/gjra  

Cite This Article:

A REVIEW ON SOLID DISPERSION MULTILAYERED CAFEINE-CURCUMIN GRANULATED TABLET, Simanchal Panda GLOBAL JOURNAL FOR RESEARCH ANALYSIS : Volume-9 | Issue-1 | January-2020

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