A RANDOMIZED PROSPECTIVE COMPARATIVE STUDY OF KETAMINE NEBULIZATION VERSUS SALINE NEBULIZATION IN REDUCING THE INCIDENCE OF POST OPERATIVE SORE THROAT IN PATIENTS UNDERGOING ENDOTRACHEAL INTUBATION.

Dr Renu Devaprasath; Dr S.Nishal Perumal; Dr Unnikrishnan.C.P; Dr Hariprasad

Volume : VIII, Issue : V, May - 2019

A RANDOMIZED PROSPECTIVE COMPARATIVE STUDY OF KETAMINE NEBULIZATION VERSUS SALINE NEBULIZATION IN REDUCING THE INCIDENCE OF POST OPERATIVE SORE THROAT IN PATIENTS UNDERGOING ENDOTRACHEAL INTUBATION.

Dr Renu Devaprasath, Dr S. Nishal Perumal, Dr Unnikrishnan. C. P, Dr Hariprasad

Abstract :

BACKGROUND: Postoperative Sore Throat (POST) is a common adverse event occurring after general anaesthesia with endotracheal tube. This study is done to find out the effectiveness of ketamine nebulization in decreasing the incidence and severity of postoperative sore throat. STUDY DESIGN: A prospective, double-blind, randomized, comparative study. MATERIAL AND METHODS : 64 ASA I and II patients who underwent elective surgeries under general anaesthesia at Dr Jeyasekharan Hospital and Nursing Home, were randomly divided into two groups. Group K (n=32) received ketamine and group S received saline nebulization pre op. Postoperative sore throat was observed using a 4 point pain scale. RESULTS: The incidence of sore throat at 4 hours postop was 46.90% (group S) when compared to 12.50% (group K). There was no evidence of significant hemodynamic changes, emergence delirium or nausea/vomiting associated with ketamine nebulization. CONCLUSIONS: The incidence and severity of sore throat in patients who received ketamine were significantly less compared to saline nebulization after general anaesthesia with endotracheal intubation.