A PROSPECTIVE STUDY OF PEPTIC PERFORATION IN BUNDELKHAND REGION IN REFERENCE TO PREVALENCE OF HELICOBACTER PYLORI IN PEPTIC PERFORATION

Dr. Ramesh Chandra Arun; Dr. Surya Prakash

Volume : VIII, Issue : VII, July - 2019

A PROSPECTIVE STUDY OF PEPTIC PERFORATION IN BUNDELKHAND REGION IN REFERENCE TO PREVALENCE OF HELICOBACTER PYLORI IN PEPTIC PERFORATION

Dr. Ramesh Chandra Arun, Dr. Surya Prakash

Abstract :

Purpose: The main aims of study were-Peptic perforation in reference to prevalence of H. pylori infection, age distribution of the patients with peptic perforation, sex distribution of H.pylori in peptic perforation, size and site of perforation, residential living of the patients. Method: A total of 51 Patients who were diagnosed as a case of peptic perforations, were included in this prospective study conducted in the Department of surgery, Maharani Laxmi Bai Medical College, Jhansi over a period of June 2015 to July. 2017. Proper history, preoperative assessment, intra-operative evaluation and biopsy were taken and Rapid ureas test (RUT) was done. Results: Highest incidence of perforated peptic ulcer was between 31 to 60 years, 70.58% of patients fell in this group. The mean age of presentation was 40 years. Male to female ratio in peptic perforation was 5:1. 70.58% patients were smokers and (60.78%) patients were drinker. 32 (62.74%) were rural and rest of 19 (37.25%) were urban residents. Size of perforation is less than 1 cm in 41 (80.39%) patients and 1 to 2 cm in 10 (19.60%) patients. In present study patients presenting with acute perforation of peptic ulcer, prevalence of H. pylori is 92.15%. Conclusion: In this study perforated peptic ulcers are clearly associated with H. pylori infection as a strong etiological factor. Most common peptic perforation was prepyloric perforation. Commonest age of presentation of peptic perforation in Bundelkhand region was 30-60 years. Three decades after the discovery of Hp, the etiologies of bleeding peptic ulcers are changing. However, diagnosis of Hp infection is still the rst priority in these patients. Invasive RUT is most frequently used