A Comparative Study on Minimum Intubating dose of Succinylcholine

S.N. Gupta; R.K. Mehta; Rajeev Kumar; Neeraj Arora; Swati Trivedi

Volume : VI, Issue : XII, December - 2017

A Comparative Study on Minimum Intubating dose of Succinylcholine

S. N. Gupta, R. K. Mehta, Rajeev Kumar, Neeraj Arora, Swati Trivedi

Abstract :

BACKGROUND

Succinylcholine remains the gold standard and satisfactory muscles relaxants for endo tracheal intubation.

The aims of this study to assess three minimum dose of Succinylcholine for tracheal intubation as the modern balance anaesthesia consist of amnesia, analgesia & muscles relaxation.

MATERIAL & METHODS

60 adults patient of ASA grade I & II posted for elective surgery under general anaestheisa who also required endo tracheal intubation, was induced with inj. fentanyl, 2 mcg / kg. and propofol 2 mg / kg. iv.

The patient were randomly allocated in to three groups according to dose of succinylcholine [0.4 mg/kg., 0.6 mg/kg. & 1 mg/kg.]. The overall intubation condition assessed after 60 seconds of succinylcholine inj.

RESULT

The acceptable intubating condition (excellent & good grade combined) were obtained in 65%, 100%, 100% of the patient who received 0.4 mg, 0.6 mg & 1 mg/kg of Succinylcholine respectively, P<0.001, excellent intubation condition were obtained in 51%, 96% and 100% of the patient after 0.4, 0.6 and 1 mg/kg of Succinylcholine respectively P<0.001.

CONCLUSION

The 0.6 mg/kg Succinylcholine can be used as minimum intubating dose as it provide acceptable intubating condition within 60 seconds as compared to 1 mg / kg which may be excessive. Duration of action of Succinylcholine is dose dependent & reducing the dose allow a more rapid return of spontaneous respiration, reflexes and decreases the apnoea time.