A comparative study of the efficacy of Tab. Misoprostol 600 mcg (PR) with Inj. Methylergometrine0.2mg (IM) for the prevention of post-partum haemorrhage.

Dr. Sabrina Mhapankar; Dr. Rahul Khatri; Dr. Saurabh Shetty; Dr. Sushil Kumar; Dr. Bhoomika Jain; Dr. Akriti Gupta

Volume : IX, Issue : VI, June - 2020

A comparative study of the efficacy of Tab. Misoprostol 600 mcg (PR) with Inj. Methylergometrine0.2mg (IM) for the prevention of post-partum haemorrhage.

Dr. Sabrina Mhapankar, Dr. Rahul Khatri, Dr. Saurabh Shetty, Dr. Sushil Kumar, Dr. Bhoomika Jain, Dr. Akriti Gupta

Abstract :

Background- Maternal Mortality is a major challenge to health care system worldwide. Most common cause of which is post partum haemorrhage. Post-partum haemorrhage is the loss of more than 500 ml of blood within the first 24 hours of delivery or loss of any amount that is enough to cause hemodynamic instability in the mother or the loss of more than 10% of the total blood volume. The common cause of PPH is uterine atony. Purpose- The aim of this study is to compare the efficacy of the two most frequently used uterotonics, Misoprostol and Methylergometrine. And to assess the incidence of side effects associated with the use of each drug regimen. Methods- This is s Prospective, Observational study of a total of 100 consecutive registered cases undergoing vaginal deliveries, from which half of the randomly selected patients was given one Misoprostol while other group was given Methylergometrine. Conclusion- Both drugs i.e. misoprostol and methylergometrine are equally effective in prevention of postpartum haemorrhage and have same efficacy. Misoprostol is an inexpensive drug and easily available. The study intends to provide information for the review and possible revision of the current status on the management of the third stage of labor. It can also help inform policy makers on the feasibility of using Misoprostol in AMTSL (active management of third stage of labour), especially in resource poor settings where other uterotonics are unavailable or wherever AMTSL is not practiced. • Ethical approval: This article does not contain any studies with animals performed by any of the authors.